Combination Otic Formulation
OwnerDavid M. PRESTONinventor
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Abstract
A therapeutic composition and methods for the treatment and prevention of otic disorders in humans and animals comprising an analgesic agent, an anesthetic agent, a combination of an astringent and an anti-infective are disclosed. The composition and method provides for contacting the tympanic membrane without substantially penetrating the tympanic membrane. The composition and method may further comprise polycosanols, a steroidal anti-inflammatory, aloe and mixtures thereof.
Claims19
A therapeutic composition for the treatment and prevention of otic disorders in humans and animals consisting essentially of:
- a) benzocaine;
- b) antipyrine;
- c) aluminum acetate;
- d) acetic acid;
- and
- e) optionally polycosanol, an anti-inflammatory agent, aloe or combinations thereof.
A therapeutic composition for the treatment and prevention of otic disorders in humans and animals comprising:
- a) an analgesic agent;
- b) an anesthetic agent;
- and
- c) a combination of an astringent and an anti-infective;
- wherein the composition is substantially free of COX-2 inhibitors.
A method for the treatment and prevention of otic disorders in humans and animals comprising:
- contacting, without substantially penetrating, the tympanic membrane of the subject with a composition comprising:
- a) an analgesic agent;
- b) an anesthetic agent;
- c) a combination of an astringent and an anti-infective;
- and
- d) optionally with polycosanol, a steroidal anti-inflammatory or aloe,
- wherein the composition is substantially free of COX-2 inhibitors.
A method for the treatment and prevention of otic disorders in humans and animals in need thereof comprising:
- contacting, without substantially penetrating, the tympanic membrane of the subject with a composition consisting essentially of:
- a) an analgesic agent;
- b) an anesthetic agent;
- c) a combination of an astringent and an anti-infective;
- d) polycosanol;
- e) a carrier, wherein the carrier allows administration by drops placed into the external ear canal;
- and
- f) optionally an anti-inflammatory agent or aloe or combinations thereof.
A therapeutic otic composition comprising:
- a) 0.01%-10% (w/v) benzocaine;
- b) 0.01%-10% (w/v) antipyrine;
- c) 0.01%-10% (w/v) aluminum acetate;
- d) less than 2% (w/v) acetic acid;
- and
- e) optionally 0.01%-50% (w/v) polycosanol, 0.01%-5% (w/v) steroidal anti-inflammatory agent, 0.01%-10% (w/v) aloe or combinations thereof.
Dependencies are inferred from the claim text.