Heterocarpine, a plant-derived protein with anti-cancer properties
AssigneeSociete de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
InventorsEric Ferrandis, Beng Poon, Christine Sohier, Christophe Thurieau
Life of this patent
Estimating the term…
Abstract
The invention relates to a plant-derived protein with anti-cancer properties which binds the human growth hormone-releasing hormone (hGHRH). Said protein, which is obtained from the Pilocarpus Heterophyllus plant, is particularly adapted for preparing a medicament that is intended for the treatment of cancers for which growth is dependant on the GHRH growth factor and, in particular, for preparing a medicament that is intended for the treatment of cancers including small cell lung cancer and breast cancer.
Claims6
(canceled)
The method of claim 6 wherein the protein has been obtained from an extract from cells of the plant Pilocarpus Heterophyllus cultured in vitro.
The method of claim 6 wherein the cancers dependent on the growth factor GHRH are small-cell lung cancer or breast cancer.
A method of treating a cancer dependent on growth factor GHRH in warm-blooded animals comprising administering to warm-blooded animals in need thereof an amount of an isolated protein obtained by extraction of Pilocarpus Heterophyllus, said protein having a molecular mass of approximately 90.9 kDa and comprises fragments of peptide sequences SEQ ID NO:1, SEQ ID NO:2 and SEQ ID NO:3 and being able to be presented in a glycosylated or non-glycosylated form sufficient to treat said cancer.
Dependencies are inferred from the claim text.