Back to results
US 2008/0167217 A1Published application
Aryl ketone compounds and compositions for delivering active agents
AssigneeEmisphere Technologies, Inc.
InventorsParshuram Rath, Maria Isabel Gomez-Orellana
Life of this patent
Estimating the term…
Abstract
The present invention provides aryl ketone compounds and compositions containing them which facilitate the delivery of active agents. The aryl ketone compounds have the formula or a salt thereof, where n=1 to 9, and R1 to R5 are independently hydrogen, C1 to C4 alkyl, C1 to C4 alkoxy, C2 to C4 alkenyl, halogen, hydroxyl, —NH—C(O)—CH3, or —O—C6H5.
Claims18
A compound selected from
- 10-(4-Hydroxy-phenyl)-10-oxodecanoic acid;
- 10-(2-Hydroxy-phenyl)-10-oxo-decanoic acid;
- 4-(4-Methoxy-phenyl)-4-oxo-butyric acid;
- 5-(4-Methoxy-phenyl)-5-oxo-pentanoic acid;
- 10-(2,5-Dihydroxy-phenyl)-10-oxo-decanoic acid;
- 5-Oxo-5-(4-Phenoxy-phenyl)-pentanoic acid;
- 5-Oxo-5-(3-Phenoxy-phenyl)-pentanoic acid;
- and
- 7-Oxo-7-(3-Phenoxy-phenyl)-heptanoic acid;
- and salts thereof.
7 more elements
A composition comprising:
- (A) at least one active agent;
- and
- (B) a compound of the formula:
- or a salt thereof, wherein
- n is an integer from 1 to 9, and
- R1 to R5 are independently hydrogen, C1 to C6 alkyl, C1 to C6 alkoxy, C2 to C6 alkenyl, halogen, hydroxyl, or —O—C6H5,
- or a salt thereof.
4 more elements
A method for preparing a composition, said method comprising mixing:
- (A) at least one active agent;
- and
- (B) at least one compound of the formula:
- or a salt thereof, wherein
- n is an integer from 1 to 9, and
- R1 to R5 are independently hydrogen, C1 to C6 alkyl, C1 to C6 alkoxy, C2 to C6 alkenyl, halogen, hydroxyl, or —O—C6H5,
- or a salt thereof.
4 more elements
Dependencies are inferred from the claim text.