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AssigneeNovozymes, Inc.
InventorsSarah Teter, Joel Cherry, Connie Ward, Aubrey Jones, Paul Harris, Jung Yi
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The present invention relates to variants of a parent glycoside hydrolase, comprising a substitution at one or more positions corresponding to positions 21, 94, 157, 205, 206, 247, 337, 350, 373, 383, 438, 455, 467, and 486 of amino acids 1 to 513 of SEQ ID NO: 2, and optionally further comprising a substitution at one or more positions corresponding to positions 8, 22, 41, 49, 57, 113, 193, 196, 226, 227, 246, 251, 255, 259, 301, 356, 371, 411, and 462 of amino acids 1 to 513 of SEQ ID NO: 2 a substitution at one or more positions corresponding to positions 8, 22, 41, 49, 57, 113, 193, 196, 226, 227, 246, 251, 255, 259, 301, 356, 371, 411, and 462 of amino acids 1 to 513 of SEQ ID NO: 2, wherein the variants have glycoside hydrolase activity. The present invention also relates to nucleotide sequences encoding the variant glycoside hydrolases and to nucleic acid constructs, vectors, and host cells comprising the nucleotide sequences.
An isolated variant of a parent glycoside hydrolase, comprising a substitution at a position corresponding to position 205 of amino acids 1 to 513 of SEQ ID NO:
A method for obtaining a variant of a parent glycoside hydrolase, comprising:
An isolated polypeptide having glycoside hydrolase activity, wherein the amino acid sequence of the polypeptide differs at a position corresponding to position 205 of amino acids 1 to 513 of SEQ ID NO:
Dependencies are inferred from the claim text.