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US 2008/0166810 A1Published application
Systems for genome selection
AssigneeSearete LLC, a limited liability corporation of the State of Delaware
InventorsW. Daniel Hillis, Roderick A. Hyde, Edward K.Y. Jung, Robert Langer, Nathan P. Myhrvold, Lowell L. Wood
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Abstract
Systems, methods, compositions and apparatus relating to genome selection are disclosed.
Claims71
A method comprising:
- hybridizing one or more probes in vitro to one or more nucleic acid sequences of one or more male germ line haploid genomes;
- determining one or more genetic characteristics of the one or more male germ line haploid genomes;
- and
- selecting one or more of the one or more male germ line haploid genomes based at least partially on one or more of the one or more genetic characteristics of the one or more male germ line haploid genomes.
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An apparatus comprising:
- one or more sourcing units including one or more first sources of one or more male germ line haploid genomes and one or more second sources of one or more probes;
- one or more hybridization units operable to co-localize one or more of the one or more probes with one or more nucleic acids of the one or more male germ line haploid genomes;
- one or more monitoring units operable to detect one or more of the one or more probes hybridized to the one or more nucleic acids of the one or more male germ line haploid genomes;
- and
- one or more controller units operable to select one or more of the one or more male germ line haploid genomes at least partially based on the detection of one or more of the one or more probes hybridized to the one or more nucleic acids.
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An apparatus comprising:
- one or more characterization units operable to detect one or more probes hybridized to one or more nucleic acids of one or more male germ line haploid genomes;
- and
- one or more controller units operable to select one or more of the one or more male germ line haploid genomes at least partially based on the detection of one or more of the one or more probes hybridized to the one or more nucleic acids.
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Dependencies are inferred from the claim text.