Human toll homologues
AssigneeGenentech, Inc.
InventorAustin Gurney
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Abstract
The invention relates to the identification and isolation of novel DNAs encoding the human Toll proteins PRO285 and PRO286, and to methods and means for the recombinant production of these proteins. The invention also concerns antibodies specifically binding the PRO285 or PRO286 Toll protein.
Claims26
Isolated nucleic acid comprising DNA encoding a PRO285 polypeptide having amino acid residues 1 to 839 of FIG. 1 (SEQ ID NO:1).
Isolated nucleic acid comprising DNA encoding a PRO286 polypeptide having amino acid residues 1 to 825 of FIG. 3 (SEQ ID NO:3).
A chimeric molecule comprising a PRO285 or PRO286 polypeptide or a transmembrane-domain deleted or inactivated variant thereof, fused to a heterologous amino acid sequence.
An antibody which specifically binds to a PRO285 or PRO286 polypeptide.
Dependencies are inferred from the claim text.