Method of Producing an Antibody Using a Cell in Which the Function of Fucose Transporter Is Inhibited
OwnerMasayuki Tsuchiya, Shigeyuki IIjima +4inventors
InventorsMasayuki Tsuchiya, Shigeyuki IIjima, Izumi Sugo, Yasuo Sekimori, Kiyoshi Habu, Masamichi Sugimoto
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Abstract
The present invention relates to a method of producing a recombinant protein particularly an antibody using a cell in which the function of a fucose transporter is inhibited. According to the present invention, a cell in which the expression of fucose transporter genes on both homologous chromosomes is artificially suppressed is provided.
Claims15
A cell, in which the expression of fucose transporter genes on both chromosomes is artificially suppressed.
A method for inhibiting the addition of fucose to a protein, comprising artificially suppressing the expression of fucose transporter genes on both chromosomes upon production of a recombinant protein using a cell.
Dependencies are inferred from the claim text.