Back to results
US 2008/0166747 A1Published application
Biosensor
AssigneeDuke University
InventorsHomme W. Hellinga, Loren L. Looger
Life of this patent
Estimating the term…
Abstract
Biosensors are made by attaching covalently or non-covalently at least one reporter group to one or more specific positions of a bacterial periplasmic binding protein (bPBP). Upon binding of ligand to the biosensor, there is a change in the signal transduced by the reporter group.
Claims22
A biosensor for ligand, which comprises a glucose binding protein (GBP) and at least one reporter group attached at position 183 of said GBP, wherein binding of glucose in a glucose-binding pocket of said biosensor causes a change in signaling by said reporter group.
3-6. (canceled)
(canceled)
21-22. (canceled)
Dependencies are inferred from the claim text.