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US 2008/0166717 A1Published application
Angiopoietin-like 2 as a biomarker of vascular endothelial cell abnormal function and senescence
AssigneeInstitut de Cardiologie de Montreal
InventorEric Thorin
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Abstract
A method for assessing a physiological state of a mammal. The method includes: obtaining from the mammal a biological sample; measuring the expression of angiopoietin-like 2 in the biological sample; and assessing the physiological state of the mammal by comparing the measured expression of the angiopoietin-like 2 to a predetermined normal expression level in normal subjects, wherein an increase in angiopoietin-like 2 level over the predetermined normal expression level indicates an abnormal physiological state.
Claims20
A method for assessing a physiological state of a mammal, said method comprising:
- obtaining from the mammal a biological sample;
- measuring the expression of angiopoietin-like 2 in the biological sample;
- and
- assessing the physiological state of the mammal by comparing the measured expression of the angiopoietin-like 2 to a predetermined normal expression level in normal subjects, wherein an increase in angiopoietin-like 2 level over the predetermined normal expression level indicates an abnormal physiological state.
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Dependencies are inferred from the claim text.