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US 2008/0166433 A1Published application
Methods and Composition For Dietary Supplements
AssigneeVDF Futureceuticals, Inc.
InventorsDusan Miljkovic, Jovan Hranisavljevic
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Abstract
Compositions and methods are provided to reduce glucose concentration in an organism. Particularly contemplated compositions include a compound that binds to a thaumatin-like protein and that is isolated from a plant. Contemplated compositions further reduce blood lipid concentrations at the concentration effective to reduce the glucose concentration.
Claims16
1-37. (canceled)
A method of reducing a concentration of blood glucose in a human, comprising:
- preparing a plant extract from hordeum vulgare in a process that includes
- (a) malting barley grains, (b) subjecting the malted barley grains to a first salt extraction to obtain a crude extract, (c) refining the crude extract by solvent extraction to form a first refined extract;
- or
- (d) malting barley grains, (e) subjecting a soluble fraction of the malted barley grains to a chromatographic step to obtain a crude extract that includes a thaumatin-like protein, (f) refining the crude extract by size fractionation to form a second refined extract;
- wherein the steps (a)-(c) or (d)-(f) are selected such that the first or second refined extract provide a composition that includes a compound that binds to a thaumatin-like protein;
- and
- administering the composition to the organism in a dosage effective to decrease the concentration of glucose.
4 more elements
Dependencies are inferred from the claim text.