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US 2008/0166404 A1Published application
Bioadhesive drug formulations for oral transmucosal delivery
AssigneeAcelRx Pharmaceuticals, Inc.
InventorsStelios Tzannis, Larry Hamel, Pamela Palmer, Thomas Schreck, Andrew I. Poutiatine
Life of this patent
Estimating the term…
Abstract
Bioadhesive drug formulations that adhere to an oral mucosal membrane of a subject are provided together with single dose applicators and devices for delivering the drug formulations to the oral mucosa, and methods for using the same.
Claims26
1-92. (canceled)
A bioadhesive formulation for sublingual administration to a subject as a solid dosage form, comprising:
- (a) a non-ordered mixture of a pharmaceutically active amount of a drug;
- (b) a bioadhesive material, said bioadhesive material providing for adherence to the oral mucosa of said subject;
- and
- (c) stearic acid.
1 more element
A bioadhesive formulation for sublingual administration to a subject as a solid dosage form, comprising:
- (a) a non-ordered mixture of a pharmaceutically active amount of a drug;
- (b) a bioadhesive material, said bioadhesive material providing for adherence to the oral mucosa of said subject, wherein dissolution of said drug formulation is independent of pH over a pH range of about 4to 8.
Dependencies are inferred from the claim text.