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AssigneePAT GmbH
InventorWOLFGANG STREMMEL
Estimating the term…
The use of therapeutically active lipids for organ/tissue-specific enrichment for the treatment of inflammatory, ischemic or degenerative disorders and/or for stimulating a regeneration is arranged and developed such that the lipids are bound on application to carrier molecules for which cell-specific uptake systems in the cells of the organs and/or tissue exist. In addition, a method of producing organ/tissue-specific therapeutically active lipids for treatment of inflammatory, ischemic or degenerative disorders and/or stimulation of a regeneration, in particular for treating inflammatory liver disorders, is claimed, which is arranged and developed such that lysophosphatidylethanolamine (LysoPE) is coupled to the carboxyl group of ursodeoxycholate (UrsoDOCA) converted to an ester to give a LysoPE-DOCA compound.
A method of organ-/tissue-specific enrichment to treat inflammatory, ischemic, or degenerative diseases and/or to stimulate regeneration, said method comprising applying therapeutically effective lipids, wherein during application the lipids are bonded to carrier molecules, for which cell-specific absorption systems exist in the cells of the organs and/or the tissues.
A method of organ-/tissue-specific enrichment, said method comprising applying therapeutically effective lipids by at least one of direct, inhalation, drop-wise, oral, intravenous, or intraperitoneal application, wherein during application the lipids are bonded to carrier molecules, for which cell-specific absorption systems exist in the cells of the organs and/or the tissues, and wherein the organ-/tissue-specific enrichment is used to treat at least one of inflammatory, ischemic, or degenerative diseases of the skin, the muscles, the reticulo-endothelial system (RES), the lymphatic system, endocrinal organs, the peripheral nervous system, the lung, the prostate, the bile tract, the pancreas, the intestines, the bones, or the joints.
A method for producing organ-/tissue-specific therapeutically effective lipids for treating inflammatory, ischemic, or degenerative diseases and/or to stimulate regeneration, particularly for treating inflammatory liver diseases, said method comprising coupling lyso-phosphatidyl ethanolamine (LysoPE) to a carboxyl group of ursodeoxycholate (UrsoDOCA) converted into an ester to form a LysoPE-DOCA-compound.
Dependencies are inferred from the claim text.