Nucleic acid cancer immunotherapy
AssigneeThe Penn State Research Foundation
InventorsWaldemar Debinski, Neil Christensen, Akiva Mintz
Life of this patent
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Abstract
A method for stimulating a immune response against IL-13Rα2 in a subject having or at risk for developing a disease having cells expressing IL-13Rα2 includes the steps of formulating the anti-cancer vaccine outside of the subject and administering the vaccine to the subject in an amount sufficient to stimulate an immune response against IL-13Rα2 in the subject. A composition for stimulating a immune response against IL-13Rα2 in a subject having or at risk for developing a disease having cells expressing IL-13Rα2 includes an isolated agent that can stimulate immune response against IL-13α2.
Claims12
A method for stimulating an immune response against IL-13Rα2 in a subject having or at risk for developing a disease having cells expressing IL-13Rα2, the method comprising the steps of:
- (a) formulating an anti-cancer vaccine outside of the subject, the vaccine comprising an agent that can stimulate an immune response against IL-13Rα2 when administered to an animal and an adjuvant;
- and
- (b) administering the vaccine to the subject in an amount sufficient to stimulate an immune response against IL-13Rα2 in the subject.
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Dependencies are inferred from the claim text.