Cancer Vaccine Preparation
AssigneeImmuno Frontier, Inc.
InventorsHiroshi Shiku, Shin-ichi Kageyama
Life of this patent
Estimating the term…
Abstract
A preparation combining a complex of a cancer antigen and a hydrophobized polysaccharide with an agent, e.g., an extract from hemolytic streptococcus, which binds to a Toll-like receptor to stimulate the antigen presenting cells activates all of the antigen presenting cells, the killer T cells and the helper T cells which are major immune cells when antigen specific immunity against cancer cells is induced and activated, and exerts a potent vaccinal effect. A vaccine preparation of the present invention induces immune responses to the cancer antigen, in particular, has effects of activation and induction of cytotoxic T cells and helper T cells, and thus, can be used as a therapeutic or preventive vaccine for cancer therapy.
Claims12
A cancer vaccine preparation combining an agent which is a complex of a cancer antigen protein and a hydrophobized polysaccharide with an agent which binds to a Toll-like receptor to stimulate an antigen presenting cell.
A two-drug kit independently formulating an agent which is a complex of a cancer antigen protein and a hydrophobized polysaccharide and an agent which binds to a Toll-like receptor to stimulate an antigen presenting cell.
A method for augmenting a cancer vaccinal effect characterized by substantially simultaneously or continuously administering an agent which is a complex of a cancer antigen protein and a hydrophobized polysaccharide and an agent which binds to a Toll-like receptor to stimulate an antigen presenting cell.
Dependencies are inferred from the claim text.