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US 2008/0166358 A1Published application
Quinazoline derivatives and methods of treatment
AssigneeConcert Pharmaceuticals, Inc.
InventorRoger Tung
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Abstract
This invention relates to novel quinazoline derivatives, and their pharmaceutically acceptable salts. The invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions beneficially treated by inhibiting cell surface tyrosine receptor kinases.
Claims33
A compound of formula I:
- or a pharmaceutically acceptable salt of said compound, wherein:
- each Y is independently selected from hydrogen or deuterium;
- each Z is independently selected from hydrogen or deuterium;
- and at least one Y or Z is deuterium.
1 more element
A compound of Formula IA:
- or a pharmaceutically acceptable salt thereof, wherein each Y and each Z is independently selected from hydrogen and deuterium.
Dependencies are inferred from the claim text.