Lyophilised Preparation Comprising Antibodies Against The EFG Receptor
OwnerHanns-Christian Mahler, Hans-Peter Zobel +5inventors
InventorsHanns-Christian Mahler, Hans-Peter Zobel, Robert Muller, Christiane Bachmann, Udo Haas, Margarete (heir Ludwig Kruger) Kruger, Ulrike Martini-Marr
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Abstract
The invention relates to a lyophilised pharmaceutical preparation comprising an antibody against the endothelial growth factor receptor (EGF receptor). The preparation has increased storage stability, even at elevated temperatures, and, after reconstitution, can be used parenterally for the treatment of tumours.
Claims20
1-15. (canceled)
A lyophilised pharmaceutical preparation of Cetuximab or Matuzumab, comprising
- Cetuximab or Matuzumab,
- a sugar or an amino sugar,
- an amino acid, and
- a surfactant.
A lyophilised pharmaceutical preparation of Cetuximab or Matuzumab, consisting essentially of
- Cetuximab or Matuzumab,
- a sugar or amino sugar,
- an amino acid,
- a buffer, and
- a surfactant.
Dependencies are inferred from the claim text.