Back to results
US 2008/0166266 A1Published application
Method and Apparatus for Cleaning of Viable Donor Soft Tissue
AssigneeNovasterilis, Inc.
InventorsDavid C. Burns, Anthony R. Eisenhut, Renee Christopher
Life of this patent
Estimating the term…
Abstract
A process for cleaning donor soft tissue by removing contaminants by extraction using a fluid at supercritical temperature and pressures while preserving the integrity of the tissue.
Claims8
A process for cleaning donor soft tissue to preserve the integrity of the soft tissue comprising:
- obtaining a donor soft tissue;
- mechanically removing external lipids and other organic material on the surface of the soft tissue;
- cutting the soft tissue into the desired size and shape to form a tissue part;
- placing tissue part and an absorbent material into a gas permeable package and sealing the package;
- placing the package into a reactor pressure vessel;
- introducing supercritical carbon dioxide fluid to the pressure vessel;
- maintaining the tissue part in contact with the fluid while mechanically agitating the fluid for a time sufficient to impregnate the tissue part with carbon dioxide and to extract excessive organic matter from the tissue part;
- and
- removing the tissue part from the package and separating from the absorbent material and rinsing the tissue part with a sterile solution.
6 more elements
A process for cleaning donor soft tissue to preserve the integrity of the soft tissue comprising:
- obtaining a donor soft tissue;
- mechanically removing topical contaminants from the surface of the soft tissue;
- placing the soft tissue and an absorbent material into a gas permeable package and sealing the package;
- placing the package into a reactor pressure vessel;
- introducing supercritical fluid into the pressure vessel;
- maintaining contact between the supercritical fluid and the soft tissue in the package while mechanically agitating the fluid for a time sufficient to solubilize contaminants contained in the soft tissue and separate the contaminants from the soft tissue by absorption into the absorbent material;
- and
- removing the package from the pressure vessel, separating the tissue from the absorbent material in the package and rinsing the tissue with a sterile solution.
5 more elements
A process for cleaning donor soft tissue to preserve the integrity of the soft tissue comprising:
- obtaining a donor soft tissue;
- placing the soft tissue and an absorbent material into a gas permeable package and sealing the package;
- placing the package into a reactor pressure vessel;
- introducing a supercritical extractant fluid capable of extracting excessive organic matter from the soft tissue into the pressure vessel;
- maintaining contact between the supercritical extractant fluid and soft tissue for a time sufficient to impregnate the soft tissue with the supercritical extractant fluid and extracting excessive organic matter from the soft tissue;
- and
- recovering the soft tissue from the package and separating the soft tissue from the absorbent material in the package.
4 more elements
Dependencies are inferred from the claim text.