Method and device for mixing samples on a support
AssigneeRoche Diagnostics Operations, Inc.
InventorsKarl-Heinz Mann, Thomas Mayer, Friedhelm Vieth
Life of this patent
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Abstract
A method for detecting analytes in a liquid is provided in which the liquid is subjected to a mixing treatment on an area of a support which has in particular immobilized reactants, wherein in the mixing treatment the liquid is impinged upon by a stream of gas that sweeps across at least some areas of the support surface in a scanning manner by means of a jet directed towards the support surface. The invention also concerns a method for mixing a liquid sample comprising an analyte and a device for carrying out the method.
Claims19
A method for mixing a liquid sample comprising an analyte, the method comprising:
- providing a trough-shaped vessel as a support comprising a bottom area and containing a reactant and the sample,
- providing a stream of gas that impinges in vertical orientation upon the liquid sample by means of a jet vertically directed toward the bottom area, and
- generating a relative movement between the jet and the vessel, so that the stream of gas sweeps across at least a part of the bottom area in a scanning manner, thereby causing a mixing of the liquid sample.
A method for mixing a liquid sample comprising an analyte, the method comprising:
- providing a support comprising an area comprising a reactant immobilized thereon and the sample, wherein the sample wets the area, and
- providing a stream of gas that impinges upon and sweeps across at least a part of the area in a scanning manner, the stream of gas being provided by means of a jet directed toward the area wherein relative movement between the jet and the support provides a mixing of the liquid sample and thereby causing the analyte to be available for reaction with the immobilized reactant.
A method for detecting an analyte in a liquid sample comprising:
- providing a support comprising an area comprising a reactant immobilized thereon and the sample, wherein the sample wets the area,
- providing a stream of gas that impinges upon and sweeps across at least a part of the area in a scanning manner, the stream of gas being provided by means of a jet directed toward the area wherein relative movement between the jet and the support provides a mixing of the liquid sample and thereby causing the analyte to be available for binding with the immobilized reactant, and
- detecting the binding of the analyte with the immobilized reactant.
Dependencies are inferred from the claim text.