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US 2008/0113382 A1Published application
Device and Method for Detecting the Presence of Hemoglobin in a Biological Sample
AssigneeEnterix Pty Limited
InventorHoward Milne Chandler
Life of this patent
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Abstract
A device and method for detecting the presence of hemoglobin in a biological sample, more particularly, the presence of blood in a fecal sample as an indicator of upper or lower gastrointestinal tract bleeding.
Claims22
A device for the detection of hemoglobin in a biological sample, comprising a carrier matrix which includes:
- (i) a sample application region for receipt of said biological sample;
- (ii) a substrate region in liquid-conductive communication with, or combined with, the sample application region and having a pseudoperoxidase substrate applied thereto or impregnated therein, said pseudoperoxidase substrate comprising a peroxide or hydroperoxide reagent;
- and
- (iii) an indicator region in liquid-conductive communication with, or combined with, the substrate region and having an indicator applied thereto or impregnated therein, said indicator producing a detectable response in the presence of heme and said pseudoperoxidase substrate.
1 more element
A method for the detection of hemoglobin in a biological sample, comprising the steps of:
- (i) applying said biological sample to a sample application region of a carrier matrix which comprises said sample application region, a substrate region and an indicator region;
- (ii) contacting said biological sample with the substrate region wherein said sample is contacted with a pseudoperoxidase substrate comprising a peroxidase or hydroperoxidase reagent;
- and
- (iii) contacting said sample and pseudoperoxidase substrate with the indicator region wherein said sample and substrate are contacted with an indicator which produces a detectable response in the presence of heme and said pseudoperoxidase substrate.
1 more element
Dependencies are inferred from the claim text.