Causative agent of the mystery swine disease, vaccine compositions and diagnostic kits
AssigneeBoehringer Ingelheim Vetmedica GmbH
InventorsGert WENSVOORT, Catharinus Terpstra, Joannes Pol, Robertus Moormann, Johanna Meulenberg
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Abstract
Composition of matter comprising the causative agent of Mystery Swine Disease, Lelystad Agent, in a live, attenuated, dead, or recombinant form, or a part or component of it. Vaccine compositions and diagnostic kits based thereon. Recombinant nucleic acid comprising a Lelystad Agent-specific nucleotide sequence. Peptides comprising a Lelystad Agent-specific amino acid sequence. Lelystad Agent-specific antibodies.
Claims6
A method of producing an immunogenic composition, the method comprising:
- introducing a purified preparation containing a polynucleotide encoding at least one polypeptide encoded by one or more open reading frames (ORFs) of ORFs 1-7 of a mystery swine disease virus, into a suitable host cell,
- culturing said suitable host cell;
- and
- isolating one of the following therefrom;
- a suitable host cell containing said polypeptide;
- virus;
- viral protein;
- viral polynucleic acid;
- or mixtures thereof
The method according to claim I, further comprising isolating at least of a cultured host cell and a polypeptide encoded by said polynucleotide.
-10. (canceled)
Dependencies are inferred from the claim text.