Pre-Clinical Animal Testing Method
AssigneeMicroCHIPS, Inc.
InventorsJohn Santini, Dennis Ausiello
Life of this patent
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Abstract
Devices and methods are provided for wirelessly powering and/or communicating with implanted medical devices used for the controlled exposure and release of reservoir contents, such as drugs or sensors. The device may include a substrate having a plurality of reservoirs containing reservoir contents for release or exposure; and a rechargeable or on-demand power source comprising a local component which can wirelessly receive power from a remote transmitter wherein the received power can be used, directly or following transduction, to activate the release or exposure of the reservoir contents.
Claims13
1-27. (canceled)
A method of conducting a pre-clinical animal study comprising the steps of:
- (a) implanting into a non-human test animal a device which comprises:
- (1) a substrate,
- (2) a plurality of discrete reservoirs located in the substrate, each reservoir having at least one opening,
- (3) molecules disposed within the reservoirs,
- (4) a plurality of reservoir caps, each closing off the at least one opening of each of the reservoirs, and
- (5) activation means for selectively disintegrating or permeabilizing each said reservoir cap to expose the molecules in the reservoir;
- (b) exposing, via the activation means, at least a first amount of the molecules to a physiological fluid of the test animal;
- and
- (c) monitoring one or more physiological parameters of the test animal following exposing of the molecules.
Dependencies are inferred from the claim text.