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US 2008/0077375 A1Published application
Integrated Biosensor and Simulation System for Diagnosis and Therapy
OwnerDennis Fernandezinventor
Life of this patent
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Abstract
BioMEMS/NEMS appliance biologically monitors an individual, using biosensors to detect cellular components. Data is simulated or analyzed using systems-biology software, which provides diagnostic or therapeutic guidance.
Claims23
A computer-based method for predicting therapeutic strategy comprising the steps of:
- representing one or more biological processes and molecular interactions as mathematical models;
- accessing a systems biology platform via a network to said modeled biological processes and molecular interactions in a biological system, wherein the systems biology platform comprises genomics database, transcriptomics database, proteomics database, metabolomics database, pharmacogenomics database, pharmacokinetics database, disease database or drug database;
- running a set of simulations based on the data in the models and administration of a drug;
- and
- generating a simulation report for predicting outcome of the interactions with the drug, thereby aiding in target discovery and validation.
2 more elements
A computer-based method to assist in medical decision-making comprising the steps of:
- accessing electronically a storage via a network, wherein the storage comprises genomics database, proteomics database, pharmacogenomics database, metabolomics database, pharmacokinetics database, transcriptomics database, disease database or drug database;
- and
- implementing knowledge-based techniques in a systems biology platform to provide therapy, diagnosis or other automated feedback.
A system for computational modeling of disease in a biological host comprising:
- a processor and a memory wherein the memory represents mathematically, via a network, genomic, transcriptomic, metabolomic, pharmacogenomic or pharmacokinetic data;
- runs one or more simulations to analyze biological interactions and predicts the effect of a drug on biological molecules in the host, thereby aiding target discovery and validation.
Dependencies are inferred from the claim text.