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US 2008/0076809 A1Published application
Heterocyclic compound for stimulating or inducing the growth of the hair or eyelashes and/or slowing down their loss composition comprising it and its uses
AssigneeSociete L'Oreal S.A.
InventorsChristophe Boulle, Roger Rozot, Maria Dalko
Life of this patent
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Abstract
The invention relates to a composition for caring for or making up keratinous fibers comprising a heterocyclic compound of formula (I) or of one of its salts: in which: Hy is a heterocycle of 4 to 7 atoms comprising a carbonyl functional group and/or a thiocarbonyl functional group and optionally being substituted and G, R1, R2 and R3 are defined in the description.
Claims19
A composition for caring for or making up keratinous fibers comprising a physiologically acceptable medium and an effective amount of at least one heterocyclic compound of formula (I) or of one of its salts, having the formula:
- wherein:
- Hy represents a heterocycle with 5 atoms comprising at least one carbonyl functional group and/or one thiocarbonyl functional group, the said heterocycle optionally being substituted by at least one substituent selected from the group consisting of saturated and unsaturated, linear and branched C1-C20 alkyl radicals;
- G represents O, S or NH;
- and
- R1, R2 and R3 represent, independently of one another, hydrogen, halogen, OR0, SR0, NR0R0′, COR0, CSR0, NR0CONR0′R0″, C(═NR0)R0′, C(═NR0)NR0′R0″, NR0C(═NR0′)NR0″R0′″, OCOR0, COSR0, SCOR0, CSNR0R0′, NR0CSR0′, NR0CSNR0′R0″, COOR0, CONR0R0′, CF3, NO2, CN, NR0COR0′, SO2R0′, SO2NR0R0′or NR0SO2R0′, or a saturated or unsaturated, linear or branched C1-C20 alkyl radical optionally substituted by R0, where R0, R0′, R0″ and R0′″, which are identical or different, represent hydrogen or linear or branched C1-C20 alkyl;
- said compound of formula (I) being selected from the group consisting of:
- (i) a compound having the formula (IIIa):
- wherein Z and Z′ are each 0;
- when Z and Z′ are the same as G, at least one of the R2 and R3 groups represents CF3;
- and when Z and Z′ are different from G, at least one of the R2 and R3 groups represents CF3 or COOR0 wherein R0 is H;
- (ii) a compound having the formula (VI):
- or a salt thereof, wherein Z, Z′ and G independently represent O or S;
- and at least one of the R2 and R3 groups represents hydrogen, CN, CF3, NO2, OR0, COOR0 or a saturated, linear or branched, C1-C20 alkyl radical optionally substituted by OR0 wherein R0 is H or a saturated, linear or branched, C1-C20 alkyl radical;
- (iii) a compound having the formula (VII):
- or a salt thereof, wherein Z, Z′ and G independently represent O or S;
- R represents a saturated, linear or branched, C1-C10 alkyl radical;
- and at least one of the R2 and R3 groups represents a saturated, linear or branched, C1-C20, alkyl radical, NO2 or OR0 wherein R0 is H or a saturated, linear or branched, C1-C20 alkyl radical;
- and
- (iv) a compound selected from the group consisting of:
16 more elements
A compound having the formula (VI):
- or a salt thereof, wherein Z, Z′ and G independently represent O or S;
- R2 and R3, independently of each other, represent hydrogen, halogen, OR0, SR0, NR0R0′, COR0, CSR0, NR0CONR0'R0′, C(═NR0)R0′, C(═NR0)NR0″R0″, NR0C(═NR0′)NR0″R0′″, OCOR0, COSR0, SCOR0, CSNR0R0′, NR0CSR0′, NR0CSNR0′R0″, COOR0, CONR0R0′, CF3, NO2, CN, NR0COR0′, SO2R0′, SO2NR0R0′ or NR0SO2R0′, or a saturated or unsaturated, linear or branched C1-C20 alkyl radical optionally substituted by R0, where R0, R0′, R0″ and R0′″, which are identical or different, represent hydrogen or linear or branched C1-C20 alkyl;
- provided that at least one of the R2 and R3 groups represents hydrogen, CN, CF3, NO2, OR0, COOR0 or a saturated, linear or branched, C1-C20 alkyl radical optionally substituted by OR0 wherein Ro is H or a saturated, linear or branched, C1-C20 alkyl radical.
A compound having the formula (VII):
- or a salt thereof, wherein Z, Z′ and G independently represent O or S;
- R represents a saturated, linear or branched, C1-C10 alkyl radical;
- R2 and R3 independently of each other, represent hydrogen, halogen, OR0, SR0, NR0R0′, COR0, CSR0, NR0CONR0′R0″, C(═NR0)R0′, C(═NR0)NR0′R0″, NR0C(═NR0′)NR0″R0′″, OCOR0, COSR0, SCOR0, CSNR0R0′, NR0CSR0′, NR0CSNR0′R0″, COOR0, CONR0R0′, CF3, NO2, CN, NR0COR0′, SO2R0′, SO2NR0R0′ or NR0SO2R0′, or a saturated or unsaturated, linear or branched C1-C20 alkyl radical optionally substituted by R0, where R0, R0′, R0″ and R0′″, which are identical or different, represent hydrogen or linear or branched C1-C20 alkyl;
- provided that at least one of the R2 and R3 groups represents a saturated, linear or branched, C1-C20 alkyl radical, NO2 or OR0 wherein R0 is H or a saturated, linear or branched, C1-C20 alkyl radical.
1 more element
A compound selected from the group consisting of:
Dependencies are inferred from the claim text.