Use of paullone derivatives for the production of medicaments for the treatment of mucoviscidosis and diseases related to protein addressing errors in cells

A use of paullones derivatives for the production of medicaments for the treatment of mucoviscidosis and diseases linked to a protein addressing error in cells, such derivatives being represented by the formula (I) comprising:

• Wherein
• X represents a C═O, C—S—CH3, C—S or —C—NHOH group;
• Z represents C or N;
• Y represents a phenyl or a thiazolyl residue, together with the adjacent ring;
• the ring(s) that constitute such derivatives being substituted as the case may be with one or more halogen atoms, hydroxyl, alkylenehydroxyl, alkynalkylenehydroxyl, alkynhydroxycyclohexyle, alkyle, alkoxyl, alkylenealkoxyl, alkylenecyano groups, the alkylene group being saturated or unsaturated, such C1 to C18 radicals having a straight or branched chain, the said chain being as the case may be substituted with one or more hydroxyl or amino groups, one or more trifluoromethyl groups, —COM, —COOM, or —CH2COOM group (where M represents a hydrogen atom or a C1 to C18 alkyl group with a straight or branched chain substituted as the case may be with one or more hydroxyl and/or amino groups), a nitroso or a cyano group;
• R5 represents a hydrogen atom or a C1 to C5 alkyl group
• R12 represents a hydrogen atom or a —C—CO2—(CH3)3 group, and the physiologically acceptable salts of these derivatives.