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US 2008/0076113 A1Published application
Methods for identifying and monitoring patients at risk for systemic inflammatory conditions, methods for selecting treatments for these patients and apparatus for use in these methods
OwnerGus Slotmaninventor
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Abstract
Methods of identifying, monitoring and matching patients with appropriate treatments who are at risk for developing a systemic inflammatory condition prior to development of signs and symptoms using a systemic mediator-associated physiologic test profile are provided.
Claims4
A method for predicting levels of inflammatory mediators in the treatment of systemic inflammatory conditions comprising:
- a) measuring baseline parameters of a patient;
- b) generating a systemic mediator-associated response test profile for the patient, said profile comprising one or more of the baseline parameters measured in step a);
- c) comparing the baseline parameters of the patient profile with the same patient parameters of established control profiles from patients diagnosed with a systemic inflammatory disease;
- and
- d) predicting levels of circulating inflammatory mediators based upon the comparison in step c).
2 more elements
A method for analyzing clinical trial results for a new therapeutic agent comprising
- a) measuring baseline parameters of a patient in a clinical trial receiving a new therapeutic agent;
- b) measuring baseline parameters of a patient in the clinical trial receiving a placebo;
- c) measuring outcome of the clinical trial for the patients of steps a) and b);
- d) generating, with one or more of the measured parameters, a systemic mediator-associated response test profile for the patients of steps a) and b);
- and
- e) predicting, based upon the patient profiles, what the response of each patient to the new therapeutic agent would have been prior to commencing the clinical trial thereby analyzing the clinical trial results of the new therapeutic agent.
3 more elements
Dependencies are inferred from the claim text.