Multilayer Films Including Cycloolefin Copolymer and Styrene-Butadiene Copolymer
OwnerS. Thomas Lee, P. Michael Bost +2inventors
InventorsS. Thomas Lee, P. Michael Bost, Jeffrey P. Viola, Jennifer R. Stewart
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Abstract
A packaging film or sheet having a styrene-butadiene block copolymer directly melt-bonded to at least one layer of a cyclo-olefin copolymer is disclosed. The films may be made by means of co-extrusion. The packaging film is amenable to thermoforming processes and is particularly suitable for forming blister packaging used in pharmaceutical applications.
Claims79
A film comprising:
- a first layer comprising styrene butadiene copolymer;
- a second layer comprising a cyclic olefin and disposed on said first layer;
- and
- a third layer comprising styrene butadiene copolymer and disposed on said second layer as an outermost layer of said film,
- wherein said first and third layers are substantially free of cyclic olefin and said second layer is substantially free of styrene butadiene copolymer.
A pharmaceutical package comprising:
- a base layer;
- a sealant layer disposed on said base layer;
- and
- a blister disposed on said sealant layer and formed from a film comprising;
- a first layer comprising styrene butadiene copolymer;
- a second layer comprising a cyclic olefin and disposed on said first layer;
- and
- a third layer comprising styrene butadiene copolymer and disposed on said second layer as an outermost layer of said film, wherein said first layer and third layers are substantially free of cyclic olefin and said second layer is substantially free of styrene butadiene copolymer.
A method of making a film, said method comprising the steps of:
- a) forming a first layer comprising styrene butadiene copolymer;
- b) forming a second layer comprising a cyclic olefin on the first layer;
- and
- c) forming a third layer comprising styrene butadiene copolymer on the second layer as an outermost layer of the film,
- wherein the first and third layers are substantially free of the cyclic olefin and the second layer is substantially free of styrene butadiene copolymer.
A multilayer film comprising:
- a styrene-butadiene block copolymer layer;
- and
- a cyclo-olefin copolymer layer which is directly melt-bonded to the styrene-butadiene block copolymer layer.
A method for making a multilayer film comprising co-extruding a styrene-butadiene block copolymer layer with a cyclo-olefin copolymer layer, such that the styrene-butadiene block copolymer layer is directly melt-bonded to the cyclo-olefin layer.
Blister packaging having a thermoformed blister sheet defining one or more domed receptacle portions, wherein the blister sheet is thermoformed from a multilayer film which includes a styrene-butadiene block copolymer layer that is directly melt-bonded to a cyclo-olefin copolymer layer.
A multilayer film comprising:
- a styrene-butadiene copolymer layer;
- and
- a cyclo-olefin copolymer layer which is directly melt-bonded to the styrene-butadiene copolymer layer, wherein said cyclo-olefin copolymer incorporates the residue of (i) the polycyclic structure of formula I, II, III, IV, V or VI, or (ii) the monocyclic structure of the formula VII:
- wherein R15, R16, R17, R18, R19, R20, R21 and R22 are the same or different and are H, a C6-C20-aryl or C1-C20-alkyl radical or a halogen atom, and n is a number from 2 to 10.
A method for making a multilayer film comprising co-extruding a styrene-butadiene copolymer layer with a cyclo-olefin copolymer layer, such that the styrene-butadiene copolymer layer is directly melt-bonded to the cyclo-olefin layer, wherein the cyclo-olefin copolymer incorporates the residue of (i) the polycyclic structure of formula I, II, III, IV, V or VI, or (ii) the monocyclic structure of the formula VII:
- wherein R15, R16, R17, R18, R19, R20, R21 and R22 are the same or different and are H, a C6-C20-aryl or C1-C20-alkyl radical or a halogen atom, and n is a number from 2 to 10.
Dependencies are inferred from the claim text.