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US 2008/0075833 A1Published application
Rate-reducing membrane for release of an agent
OwnerStephen Pacettiinventor
Life of this patent
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Abstract
A membrane that reduces the rate at which a therapeutic substance is released from an implantable medical device, such as a stent, is disclosed.
Claims32
A method of forming a coating for a medical device carrying an agent, comprising:
- applying a first composition including a polymer to at least a portion of a medical device to form a first coating, said polymer having a solubility parameter not greater than approximately 11.5 (cal/cm3)1/2, and
- wherein said first coating reduces the rate of release of said agent from said medical device.
A composition for forming a coating on a medical device comprising:
- (a) a solvent;
- and
- (b) a hydrophobic polymer dissolved in said solvent, wherein said polymer has an equilibrium water absorption factor of less than about 5% by weight by weight under physiological conditions.
An implantable medical device for carrying a therapeutic agent, comprising:
- a first coating including a polymeric material, said polymeric material having a solubility parameter not greater that approximately 11.55 (cal/cm3)1/2, wherein said first coating reduces the rate of release of said agent.
Dependencies are inferred from the claim text.