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OwnerKunihiro Hattori, Tetsuo Kojima +6inventors
InventorsKunihiro Hattori, Tetsuo Kojima, Taro Miyazaki, Tetsuhiro Soeda, Chiaki Senoo, Osamu Natori, Keiko Kasutani, Shinya Ishii
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The present inventors succeeded in separating bispecific antibodies that functionally substitute for ligands of type I interferon receptors comprising two types of molecules: AR1 chain and AR2 chain. Furthermore, the present inventors succeeded in producing bispecific antibodies that substitute for the enzyme reaction-accelerating function of blood coagulation factor VIII/activated blood coagulation factor VIII, which bind to both blood coagulation factor IX/activated blood coagulation factor IX and blood coagulation factor X.
A bispecific antibody that substitutes for the effect of a functional protein.
A bispecific antibody that has an activity of finctionally substituting for a ligand of a heteromolecule-comprising receptor.
An antibody recognizing both an enzyme and a substrate thereof, wherein said antibody is a bispecific antibody which fumctionally substitutes for a cofactor that enhances the enzymatic reaction.
Dependencies are inferred from the claim text.