Back to results
US 2008/0073221 A1Published application
Selective Splitting of Substituted Bisbenzylamides and Bisbenzylamines
AssigneeBASF SE
InventorsZeynep Yilmaz, Ulrich Griesbach, Klaus Ditrich
Life of this patent
Estimating the term…
Abstract
A process for the regioselective cleavage of secondary amines or amides is described.
Claims20
A process for the regioselective cleavage of secondary amines or amides, which comprises the following process steps:
- (a′) provision of at least one secondary bisbenzylamine or bisbenzylamide having at least one benzylic hydrogen atom in a solvent;
- (b′) electrochemical oxidation of the secondary amine or amide in the presence of an electrolyte salt and reaction of the electrolysis intermediate with a nucleophile, giving an electrolysis product mixture;
- (c′) work-up of the electrolysis product mixture;
- (d′) hydrolysis of the workup electrolysis product mixture.
1 more element
(canceled)
A method of regioselective oxidation comprising oxidating secondary bisbenzylamines or bisbenzylamides having at least one benzylic hydrogen atom.
A process for the regioselective cleavage of secondary amines or amides, which comprises the following process steps:
- (a″) provision of at least one secondary bisbenzylamine or bisbenzylamide having at least one benzylic hydrogen atom in a solvent, with the solvent optionally comprising a nucleophile;
- (b″) oxidation of the secondary amine or amide by means of 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ), giving an oxidation product mixture;
- (c″) reaction of the oxidation product mixture with a nucleophile.
Dependencies are inferred from the claim text.