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AssigneeUniversidade Federal de Minas Gerais
InventorsMaria PEREZ-GARCIA, Carlos DINIZ, Maria da Conceicao Ribeiro Diniz, Robson DOS SANTOS, Pierre BOUGIS, Marie EAUCLAIRE, Adriano PIMENTA, Thiago BRAGA
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The present invention relates to synthetic and recombinant peptide primary structures including an amino acid sequence selected from the group consisting of SEQ ID NOs: 1 to 12, wherein the primary structure includes an +aa-Pro-Pro amino acid in which “+aa” is Lys, Arg, His or a modified amino acid having a positive charge at physiological pH. The present invention also relates to a pharmaceutical composition including at least one peptide having a primary structure as defined above.
A peptide comprising at least one member selected from the group consisting of SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3, SEQ ID NO:4, SEQ ID NO:5, SEQ ID NO:6, SEQ ID NO:7, SEQ ID NO:8, SEQ ID NO:9, SEQ ID NO:10, SEQ ID NO:11 SEQ ID NO:12, and analogs thereof, wherein each of the analogs has a primary structure identical to one of SEQ ID NOs:
Dependencies are inferred from the claim text.