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AssigneesPioneer Hi-Bred International, Inc., E.I. du Pont de Nemours and Company, The Regents of the University of California
InventorsDaniel Altier, I.A. Ellanskaya, Jacob Gilliam, Jennie Hunter-Cevera, James Presnail, Eric Schepers, Carl Simmons, Tamas Torok, Nasser Yalpani
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Compositions and methods for protecting a plant from a pathogen, particularly a fungal pathogen, are provided. Compositions include an amino acid sequence, and variants and fragments thereof, for an antipathogenic polypeptide that was isolated from a fungal fermentation broth. Nucleic acid molecules that encode the antipathogenic polypeptides of the invention, and antipathogenic domains thereof, are also provided. A method for inducing pathogen resistance in a plant using the nucleotide sequences disclosed herein is further provided. The method comprises introducing into a plant an expression cassette comprising a promoter operably linked to a nucleotide sequence that encodes an antipathogenic polypeptide of the invention. Compositions comprising an antipathogenic polypeptide or a transformed microorganism comprising a nucleic acid of the invention in combination with a carrier and methods of using these compositions to protect a plant from a pathogen are further provided. Transformed plants, plant cells, seeds, and microorganisms comprising a nucleotide sequence that encodes an antipathogenic polypeptide of the invention are also disclosed.
An expression cassette comprising a promoter that drives expression in a plant or plant cell operably linked to a nucleotide sequence that encodes a polypeptide having antipathogenic activity, wherein the nucleotide sequence is selected from the group consisting of:
An antipathogenic composition comprising a carrier and at least one polypeptide selected from the group consisting of:
A method of screening candidate polypeptides to identify antipathogenic polypeptides, the method comprising:
Dependencies are inferred from the claim text.