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AssigneeCentral Glass Company, Limited
InventorsAkihiro Ishii, Masatomi Kanai, Yokusu Kuriyama, Manabu Yasumoto, Kenjin Inomiya, Takashi Ootsuka, Katsuhide Suto, Koji Ueda
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The present invention relates to a method of producing an optically active 1-aryl-2-fluoro-substituted ethylamine compound of the formula [2] or a salt thereof by hydrogenolysis of an optically active secondary amine compound of the formula [1] or a salt thereof in the presence of a transition metal catalyst of Group VIII [Chem. 59] [where Ar represents an aryl group; n represents an integer of 1 or 2; and * represents an asymmetric carbon] [Chem. 60] [where Ar represents an aryl group; n represents an integer of 1 or 2; and * represents an asymmetric carbon].
A method for producing an optically active 1-aryl-2-fluoro-substituted ethylamine compound of the formula [2] or a salt thereof by hydrogenolysis of an optically active secondary amine compound of the formula [1] or a salt thereof in the presence of a transition metal catalyst of Group VIII
A method of producing an optically active 1-aryl-2-fluoro-substituted ethylamine compound of the formula [4] or a salt thereof by hydrogenolysis of an optically active secondary amine compound of the formula [3] or a salt thereof in the presence of a palladium catalyst
A method of producing an optically active 1-aryl-2-fluoro-substituted ethylamine compound of the formula [6] or a salt thereof by hydrogenolysis of an optically active secondary amine compound of the formula [5] or a salt thereof in the presence of a palladium catalyst
An optically active imine of the formula [9]
An optically active secondary amine compound of the formula [1] or a salt thereof
An optically active imine of the formula [12]
An optically active secondary amine compound of the formula [3] or a salt thereof
An optically active imine of the formula [15]
An optically active secondary amine compound of the formula [5] or a salt thereof
An optically active 1-aryl-2-fluoro-substituted ethylamine compound of the formula [2] or a salt thereof
An optically active 1-aryl-2-fluoro-substituted ethylamine compound of the formula [4] or a salt thereof
An optically active 1-aryl-2-fluoro-substituted ethylamine compound of the formula [6] or a salt thereof
Dependencies are inferred from the claim text.