Process for producing optically active fluorochemical
AssigneeMitsubishi Gas Chemical Company, Inc.
InventorsShoji Hara, Tsuyoshi Fukuhara
Life of this patent
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Abstract
The present invention provides a process for producing an optically active fluoro compound represented by formula (3) through reaction between a specific fluoroamine and an optically active diol; and a process for producing an optically active fluoroalcohol through hydrolysis of the optically active fluoro compound. According to the process of the present invention, such optically active fluoro compounds and optically active fluoroalcohols can be produced at high optical purity and high yield in a simple manner. Such optically active fluoroalcohols are a useful source for producing drugs, pesticides, and other functional chemicals.
Claims6
A process for producing an optically active fluoro compound represented by formula (3) characterized in that the process comprises reacting a fluoroamine represented by formula (1) with an optically active diol represented by formula (2):
- (wherein each of R0, R1 and R2, which may be identical to or different from one another, represents a hydrogen atom, or an alkyl group or aryl group which may have a substitutent;
- and two or more groups of R0, R1 and R2 may be linked to form a ring structure;
- each of R3, R4, R5 and R6 represents a hydrogen atom, or an alkyl group or aryl group which may have a substitutent;
- R3 and R4 are different from each other;
- R5 and R6 are different from each other;
- the carbon atom to which R3 and R4 are bound is an asymmetric carbon atom;
- the carbon atom to which R4 and R5 are bound is an asymmetric carbon atom;
- and n is an integer of 0 to 3).
Dependencies are inferred from the claim text.