Methods for preparing 3-hydroxy-propionate and 1,3-propylene glycol
OwnerJing Chen, Fang Cui +3inventors
InventorsJing Chen, Fang Cui, Jianhua Liu, Chungu Xia, Jin Tong
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Abstract
The invention disclosed a method for producing 3-hydroxy-propionate and 1,3-propylene glycol by using epoxide as raw material. In the method, a transitional metal cobalt catalyst and a cocatalyst for the hydroesterification reaction among epoxide, carbon monoxide, and alcohol were chosen, and a hydrogenation catalyst for hydrogenating 3-hydroxy-propionate as well as the corresponding process conditions were selected for producing 3-hydroxy-propionate and 1,3-propylene glycol.
Claims26
A method for producing 3-hydroxy-propionate, comprising the steps of:
- providing an epoxide as raw material;
- providing a transitional metal cobalt catalyst and a cocatalyst;
- and
- reacting the epoxide, a carbon monoxide, and an alcohol in the presence of the catalyst and the cocatalyst under appropriate reaction conditions to produce 3-hydroxy-propionate (Reaction 1);
- wherein, the transitional metal cobalt catalyst includes a pure dicobalt octacarbonyl, cobalt tetracarbonyl and sodium salt thereof, a fatty alcohol solution or acetone solution of a tetracarbonyl anion, and a solution of cobalt carbonyl synthesized in situ, and
- the cocatalyst includes an organic compound promoter including pyridine, hydroxyl pyridine, quinoline, isoquinoline, and hydroxyl quinoline substituted by methyl or dimethyl, and derivatives thereof, and/or a inorganic compound promoter which is a salt of alkali metal or alkaline earth metal including sodium acetate, sodium carbonate, sodium bicarbonate, sodium dihydrogen phosphate, sodium sulfate, sodium chloride, sodium bromide, potassium chloride, potassium bromide, potassium hydrogen phosphate diformate, and lithium chloride.
A method for producing 1,3-propylene glycol, comprising the steps of:
- providing an epoxide as raw material;
- providing a transitional metal cobalt catalyst and a cocatalyst;
- reacting the epoxide, a carbon monoxide, and an alcohol in the presence of the catalyst and the cocatalyst under appropriate reaction conditions to produce 3-hydroxy-propionate (Reaction 1);
- providing a hydrogenation catalyst;
- providing hydrogen gas;
- and
- reacting the hydrogen gas with the 3-hydroxy-propionate in the presence the hydrogenation catalyst under appropriate reaction conditions to produce 1,3-propylene glycol (Reaction 2);
- wherein, the transitional metal cobalt catalyst includes a pure dicobalt octacarbonyl, cobalt tetracarbonyl and sodium salt thereof, a fatty alcohol solution or acetone solution of a tetracarbonyl anion, and a solution of cobalt carbonyl synthesized in situ,
- the cocatalyst includes an organic compound promoter including pyridine, hydroxyl pyridine, quinoline, isoquinoline, and hydroxyl quinoline substituted by methyl or dimethyl, and derivatives thereof, and/or a inorganic compound promoter which is a salt of alkali metal or alkaline earth metal including sodium acetate, sodium carbonate, sodium bicarbonate, sodium dihydrogen phosphate, sodium sulfate, sodium chloride, sodium bromide, potassium chloride, potassium bromide, potassium hydrogen phosphate diformate, and lithium chloride, and
- the hydrogenation catalyst consists of a composite oxide of titanium dioxide and silica as a carrier and cuprous chloride as an aid.
Dependencies are inferred from the claim text.