Amino alcohol compound
AssigneeSankyo Company, Limited
InventorsTakahide Nishi, Toshiyasu Takemoto, Shojiro Miyazaki, Takaichi Shimozato, Futoshi Nara, Takashi Izumi
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AssigneeSankyo Company, Limited
InventorsTakahide Nishi, Toshiyasu Takemoto, Shojiro Miyazaki, Takaichi Shimozato, Futoshi Nara, Takashi Izumi
Estimating the term…
A pharmaceutical composition is provided that has a low toxicity, demonstrates superior physicochemical properties and pharmacokinetics, and has superior peripheral blood lymphocyte count lowering activity. The pharmaceutical composition contains a compound having general formula (I): [Chemical Formula 1] (wherein R1 represents a methyl group or an ethyl group, R2 represents a methyl group or an ethyl group, and R3 represents a phenyl group substituted with 1 to 3 substituents selected from the group consisting of a halogen atom, a lower alkyl group, a cycloalkyl group, a lower alkoxy group, a halogeno lower alkyl group, a lower aliphatic acyl group and a cyano group), a pharmacologically acceptable salt thereof or a pharmacologically acceptable ester thereof.
A method for suppressing the number of peripheral blood lymphocytes comprising administering to a human in need thereof a pharmaceutically effective amount of a compound having a formula (I):
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9 to 17. (canceled)
A fumarate salt of a compound selected from the group consisting of
A method for suppressing the number of peripheral blood lymphocytes comprising administering to a warm-blooded animal in need thereof a pharmaceutically effective amount of a compound having a formula (I):
Dependencies are inferred from the claim text.