Diphenylamine-substituted salicylthiazole derivatives and related compounds as phosphotyrosine phosphatase 1b (ptb1b) inhibitors for using as blood-sugar decreasing active ingredients for treating diabetes

A compound of formula I

• Wherein:
• R1, R2, R3, R4, and R5 are, independently of one another, selected from H, F, Cl, Br, I, OH, CF3, NO2, CN, OCF3, O—(C1-C6)-alkyl, O—(C1-C4)-alkoxy-(C1-C4)-alkyl, S—(C1-C6)-alkyl, (C1-C6)-alkyl, (C2-C6)-alkenyl, (C3-C8)-cycloalkyl, O—(C3-C8)-cycloalkyl, (C3-C8)-cycloalkenyl, O—(C3-C8)-cycloalkenyl, (C2-C6)-alkynyl, aryl, O-aryl, (C1-C8)-alkylene-aryl, O—(C1-C8)-alkylene-aryl, S-aryl, CO—NH(C1-C6)-alkyl, N((C1-C6)-alkyl)2, NH—SO2—CH3, SO2—CH3, COOH, COO—(C1-C6)-alkyl, and CO—N((C1-C6)-alkyl)2;
• R6 is H, or (C1-C6)-alkyl;
• A is a bond, —CH2—, —NH—, —CH2—O—, —S—, —CH2—CH2—, or —CH(CH3)—;
• B is NH, NH(C1-C4)-alkyl, or NH(CO);
• and
• D is phenyl, or heterocycle;
• or a physiologically tolerated salt thereof.