Continuous Dosing Regimen
OwnerGary Gordon, Anne Hagey +2inventors
InventorsGary Gordon, Anne Hagey, Kysa Meek, Saul Rosenberg
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Abstract
The invention relates to pharmaceutical compositions comprising combinations of ABT-751 and anti-cancer drugs. These combinations have additive antitumorigenesis activity. This invention also relates to methods of treatment using the combinations.
Claims11
A method of treating cancer in a human comprising administering a therapeutically effective amount of N-(2-((4-hydroxyphenyl)-amino)pyrid-3-yl)-4-methoxybenzenesulfonamide and a platinum chemotherapeutic.
A composition comprising a therapeutically effective amount of a platinum chemotherapeutic and N-(2-((4-hydroxyphenyl)amino)pyridin-3-yl)-4-methoxybenzenesulfonamide.
A method of treating non-small cell lung cancer in a human comprising administering a therapeutically effective amount of N-(2-((4-hydroxyphenyl)-amino)pyrid-3-yl)-4-methoxybenzenesulfonamide and a platinum chemotherapeutic.
A method of treating cancer in a human comprising administering a therapeutically effective amount of N-(2-((4-hydroxyphenyl)-amino)pyrid-3-yl)-4-methoxybenzenesulfonamide and an antimetabolite.
A composition comprising a therapeutically effective amount of an antimetabolites and N-(2-((4-hydroxyphenyl)amino)pyridin-3-yl)-4-methoxybenzenesulfonamide.
A method of treating colon cancer in a human comprising administering a therapeutically effective amount of N-(2-((4-hydroxyphenyl)-amino)pyrid-3-yl)-4-methoxybenzenesulfonamide and 5-FU.
Dependencies are inferred from the claim text.