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US 2007/0191268 A1Published application
Recombiant lubricin molecules and uses thereof
AssigneeWyeth
InventorsCarl Flannery, Christopher Corcoran, Bethany Freeman, Lisa Collins-Racie
Life of this patent
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Abstract
Recombinant lubricin molecules and uses thereof Novel recombinant lubricin molecules and their uses as lubricants anti-adhesive agents and/or intra-articular supplements for, e.g., synvial joints, meniscus, tendon, peritoneum, pericardium and pleura are provided.
Claims35
An isolated protein comprising SEQ ID NOS:
- 9, 13, 17, 21 or 25.
An isolated protein comprising SEQ ID NO:
- 26 linked to N-2 repeat(s) of SEQ ID NO:
- 27, where N equals an integer from 3 through 200.
An isolated protein comprising SEQ ID NO:
- 26 plus SEQ ID NO:
- 28 plus [N-2 repeat(s) of SEQ ID NO:
- 27] plus SEQ ID NO:
- 29, where N equals an integer from 10 through 30.
1 more element
An isolated protein comprising SEQ ID NOS:
- 7, 11, 15, 19 or 23.
An isolated polynucleotide comprising a polynucleotide having at least 80% identity to SEQ ID NOS:
- 6, 10, 14, 18 or 22 over the entire length of the sequence.
Dependencies are inferred from the claim text.