Device and method for isolating cells, bioparticles and/or molecules from liquids
AssigneePluriselect GmbH
InventorHans Heinrich
Life of this patent
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Abstract
The invention describes an appliance and a method, with the help of which specific bio-particles, but also dissolved bio-molecules can be recognised in and separated from fluids making use of suitable carriers and known immobilisation methods. The appliance can be used both discontinuously and also for direct and continuous treatment of fluids. Fields of application of the invention are animals, bio-technology (including biological research) and medicinal diagnostics. Areas of application of the invention comprise, among others, therapy of humans, in particular direct treatment of blood.
Claims46
Appliance for the isolation of cells, bio-particles and/or molecules from fluids with the objective of an application for the treatment of human diseases, for animals, in bio-technology and medical diagnostics, comprising
- a. a reaction vessel of biocompatible material, in which a mixture of cells, particles and/or molecules is situated,
- b. functionalised micro-particles which recognize and bind the required cells, bio-particles and/or molecule-population
- c. a particle separation system based on one or more membrane(s) with pores which allow the cells, bio-particles and/or molecules, but not the micro-particles to pass,
- d. and, for continued use, various hose systems, membranes, pumps and valves, in order to be able to carry out all the actions of isolation, separation, processing and removal of the cells, bio-particles and/or molecules.
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Method for the separation of cells, bio-particles or molecules from fluids, comprising characterizing the cells, bio-particles, or molecules to be separated by specific surface-antigens;
- and separating said cells, bio-particles, or molecules.
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Dependencies are inferred from the claim text.