Concentrators for Luminescent Emission
AssigneeApplera Corporation
InventorSteven J. Boege
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Abstract
System and methods for concentrating collected flux in the form of excitation light or luminescence. The collected flux may be directed, propagated, and concentrated in various manners and may be localized into a generally small area. Concentrators may be advantageously implemented in flexible and efficient manners relative to conventional configurations where a single lens acts alone to direct the light to a detector.
Claims38
An system for illuminating a biological sample having a responsive luminescent label, the system comprising:
- an illumination source that emits energy of a type capable of a generating a response in the luminescent label;
- a concentrator that receives at least a portion of the energy emitted by the illumination source and concentrates the received energy as the energy propagates through said concentrator and wherein the concentrator is configured to emit said concentrated energy with characteristic properties;
- and
- a sample container containing the biological sample and adapted to receive the concentrated energy emitted from the concentrator wherein the concentrated energy effectuates a detectable luminescent emission arising from the label of the biological sample.
A system for detecting luminescent emissions arising from a label associated with a biological sample, the system comprising:
- a sample container containing the biological sample from which luminescent emissions arising from the label are emitted;
- a concentrator that receives at least a portion of the luminescent emissions arising from the label and concentrates the luminescent emissions they are propagated through said concentrator and wherein the concentrator is configured to emit said concentrated luminescent emissions with characteristic properties;
- and
- a detector that receives the concentrated luminescent emissions and generates a signal in response to the received concentrated luminescent emissions.
Dependencies are inferred from the claim text.