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AssigneeHenkel AG & Co. KGaA
InventorsJorg FEESCHE, Cornelius BESSLER, Stefan EVERS, Karl-Heinz MAURER, Armin EHRENREICH, Birgit VEITH, Heiko LIESEGANG, Anke HENNE, Christina HERZBERG, Gerhard GOTTSCHALK
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The invention relates to five or four novel genes and the gene products thereof from Bacillus licheniformis and sufficiently similar genes and proteins which are involved in vivo in the formation of polyamino acids. The gene in question is ywsC, ywsC′, ywtA, ywtB and ywtD or proteins coded thereby. The gene ywsC, ywsC′, ywtA and ywtB can be used to improve biotechnological production methods by microorganisms, wherein they are functionally inactivated; the gene ywtD which codes for a peptide decomposing poly-gamma glutamate can, inversely, contribute to the improvement of biotechnological production methods by increased expression. Said genes can be used positively, preferably to result in a modification or decomposition of poly-gamma glutamate.
A protein selected from the group consisting of
A nucleic acid coding for a gene product, the nucleic acid being selected from the group consisting of
A method for functional inactivation of a microorganism target gene producing a protein, the method comprising:
A method for increasing the activity of a target gene of a microorganism, the target gene producing a protein, the method comprising:
A microorganism having at least one gene having modified activity, the at least one gene being selected from the group consisting of:
Dependencies are inferred from the claim text.