Method for providing an active agent topically to the skin
OwnerRichard Bott, Mark Gebert +3inventors
InventorsRichard Bott, Mark Gebert, Paal Klykken, Isabelle Mazeaud, Xavier Thomas
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Abstract
A method of providing an active agent topically to the skin is provided and includes providing a topical preparation having an internal phase and an external phase, wherein the internal phase is dispersed within the external phase. The internal phase includes at least one hydrophilic carrier, at least one hydrophilic component, and at least one active agent, and the external phase comprises a silicone matrix. The topical preparation is placed in contact with the skin of a patient such that the active agent is released from the silicone matrix topically onto the skin of the patient.
Claims12
A method of providing an active agent comprising a protein or enzyme topically, comprising:
- providing a topical preparation, wherein said topical preparation comprises an internal phase and an external phase;
- wherein:
- said internal phase is dispersed within said external phase;
- said internal phase comprises at least one hydrophilic carrier, at least one hydrophilic component, and at least one active agent;
- and said external phase comprises a silicone matrix;
- placing said topical preparation in contact with the skin of a patient such that said active agent is released from said silicone matrix topically onto said skin of said patient.
The method as claimed in 1 further comprising:
- providing a second topical preparation comprising an internal phase and external phase, wherein said internal phase is dispersed within said external phase;
- said internal phase comprises at least one hydrophilic carrier and at least one second active agent comprising a protein or enzyme selected such that said second active agent inhibits said at least one active agent;
- said external phase comprises a silicone matrix;
- and said silicone matrix comprises a silicone adhesive;
- and
- placing said second topical preparation on said skin of said patient around said first topical preparation, wherein said skin of said patient beneath said second topical preparation is protected from said at least one active agent.
A method of providing an active agent topically, comprising:
- providing a topical preparation, wherein said topical preparation comprises an internal phase and an external phase;
- wherein said internal phase is dispersed within said external phase;
- said internal phase comprises at least one hydrophilic carrier and at least one active agent comprising a hydrolase enzyme;
- and said external phase comprises a silicone matrix;
- placing said topical preparation in contact with the skin of a patient such that said active agent is released from said silicone matrix topically onto said skin of said patient.
The method as claimed in 11 further comprising:
- providing a second topical preparation comprising an internal phase and external phase, wherein said internal phase is dispersed within said external phase;
- said internal phase comprises at least one hydrophilic carrier and at least one second active agent comprising an inhibitor for said hydrolase enzyme;
- said external phase comprises a silicone matrix;
- and said silicone matrix comprises a silicone adhesive;
- and
- placing said second topical preparation on said skin of said patient around said first topical preparation, wherein said skin of said patient beneath said second topical preparation is protected from said active agent.
Dependencies are inferred from the claim text.