Two or more solidifying agent-containing compositions and methods for dermal delivery of drugs

A method of dermally delivering a drug, comprising:

• a) applying a formulation as a layer to a skin surface of a subject, the adhesive formulation, comprising:
• i) a drug,
• ii) a solvent vehicle, comprising:
• a volatile solvent system including at least one volatile solvent, and
• a non-volatile solvent system including at one non-volatile solvent, wherein the non-volatile solvent system facilitates dermal delivery of the drug at a therapeutically effective rate over a sustained period of time, and
• iii) at least two solidifying agents,
• wherein the formulation has a viscosity suitable for application and adhesion to the skin surface prior to evaporation of the volatile solvent system;
• b) solidifying the formulation to form a solidified layer on the skin surface by at least partial evaporation of the volatile solvent system;
• and
• c) dermally delivering the drug from the solidified layer to the skin surface at therapeutically effective rates over a sustained period of time.