Buccal formulations of galanthamine and uses thereof
OwnerBodo Asmussen, Joachim Moormanninventors
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Abstract
Film-shaped medicaments for buccal administration of galanthamine or of a salt or derivative thereof comprise at least one layer which contains a cholinergic active agent acting on the central nervous system or a combination of at least two such active agents, the said substance(s) being selected from the group comprising galanthamine, pharmaceutically acceptable salts of galanthamine, galanthamine derivatives and their pharmaceutically acceptable salts.
Claims26
Film-shaped medicament for buccal administration of galanthamine or a salt or derivative thereof, said medicament comprising at least one layer which contains a cholinergic active substance acting on the central nervous system, or a combination of at least two such active substances, said active substance(s) being selected from the group consisting of galanthamine, pharmaceutically acceptable salts of galanthamine, galanthamine derivatives and their pharmaceutically acceptable salts, and said film-shaped medicament being soluble in aqueous media and/or rapidly disintegrating in aqueous media, but not being mucoadhesive.
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Use of at least one cholinergic active agent acting on the central nervous system, selected from the group consisting of galanthamine, pharmaceutically acceptable salts of galanthamine, galanthamine derivatives and their pharmaceutically acceptable salts, for the production of a film-shaped buccal medicament intended for transmucosal administration of the said active substance(s) for treating diseases or disease symptoms accompanied by, or caused by, a lack of acetylcholine-induced conduction and/or a disturbed regulation of neuronal nicotinic receptors.
Dependencies are inferred from the claim text.