Back to results
US 2007/0190103 A1Published application
Implantable medical device with surface-eroding polyester drug delivery coating
AssigneeAdvanced Cardiovascular Systems, Inc.
InventorsSyed Hossainy, Stephen Pacetti, Murthy Simhambhatla
Life of this patent
Estimating the term…
Abstract
The present invention relates to an implantable medical device comprising therapeutic agents coated on the device using polyesters for the drug reservoir layer that exhibit surface-eroding characteristics.
Claims37
An implantable medical device, comprising:
- a polymer layer comprising a biocompatible biodegradable polymer wherein the polymer layer is disposed over a surface of the medical device at a surface area to volume ratio of from about 100 mm−1 to about 1000 mm−1;
- and,
- a therapeutic agent dispersed in the polymer layer at a drug/polymer wt/wt ratio of from about 1:5 to about 5:1.
A method of treating a vascular disease comprising:
- deploying to a site in the vasculature of a patient in need thereof an implantable medical device comprising a biocompatible biodegradable polymer layer disposed over a surface thereof such that the surface area to volume ratio is from about 100 mm−1 to about 1000 mm−1, the polymer layer further comprising a therapeutic agent in a drug/polymer wt/wt ratio of from about 1:5 to about 5:1;
- and,
- releasing the implantable medical device at the site.
Dependencies are inferred from the claim text.