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AssigneeUniversity of Connecticut
InventorsAnthony DiBenedetto, Samuel Huang, Claudio Migliaresi, Antonella Motta
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A bioactive material is made using fibroin solutions and suspensions designed to support the constructions, repair, regeneration or augmentation of bone and other tissues of the body. The fibroin solutions, suspensions, and composites can be injected to fill cavities or to replace missing tissue. After injection, the materials can produce a scaffold capable of promoting tissue regeneration while degrading. The ability to inject the fibroin solutions, suspensions and composites can reduce the need for many types of surgical procedures that are used to replace or repair bone and other tissues. The fibroin solutions and suspensions are particularly useful for methods of tissue construction and/or repair.
A method of tissue construction and/or repair, comprising administering to a site to be constructed and/or repaired a fibroin solution or suspension in an amount effective to stimulate tissue formation,
A method to induce cell proliferation, comprising contacting a cell with a fibroin solution or suspension in an amount effective to induce cell proliferation,
A method of cartilage repair, comprising administering to a site in need of cartilage repair a fibroin solution or suspension in an amount effective to stimulate the cartilage repair,
Dependencies are inferred from the claim text.