Polymer Network Compositions And Associated Methods
AssigneeBoard of Regents, The University of Texas System
InventorsJames Hilt, Mark Byrne, Nicholas Peppas
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Abstract
Biomimetic polymer networks comprising a heteropolymer network having a cavity, the cavity having a selective affinity for a moiety, methods for making biomimetic polymer networks, and methods for using biomimetic polymer networks.
Claims22
A biomimetic polymer network comprising a heteropolymer network having a cavity, the cavity having a selective affinity for a moiety.
A biomimetic polymer network formed by a process comprising polymerizing a mixture comprising monomers and crosslinkers in the presence of a moiety or a target molecule or both for which a molecular imprint is to be produced, thereby forming a matrix comprising an imprint of the moiety or target molecule or both, and separating the moiety from the matrix.
A method for forming a biomimetic polymer network comprising polymerizing a mixture comprising monomers and crosslinkers in the presence of a moiety for which a molecular imprint is to be produced, thereby forming a matrix comprising an imprint of the molecule;
- and separating the moiety from the matrix.
The method of claim 110 wherein the biomimetic polymer network formed by a process of reaction injection molding or casting or extruding
A biomimetic polymer network formed by a process of reaction injection molding or casting or extruding a polymerizing mixture comprising monomers, crosslinkers, and one or more moieties, the crosslinkers added at times such that the solidification and croslinking will occur during the molding or casting or extruding;
- allowing a matrix to form which has a plurality of molecular imprints;
- and separating the moiety from the matrix.
A method for delivering a molecule comprising providing a biomimetic polymer network comprising a heteropolymer network having a cavity, the cavity having a selective affinity for a moiety;
- loading the biomimetic polymer network with a molecule by allowing a moiety present on the molecule to interact with the cavity;
- delivering the biomimetic polymer network to a desired location;
- and providing conditions that reduce the affinity of the cavity for the moiety a sufficient amount to release the molecule.
Dependencies are inferred from the claim text.