Aqueous suspension for nasal drops
AssigneeHisamitsu Medical Co., Ltd.
InventorsTakashi Narui, Toshiaki Horie
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Abstract
It is intended to provide an aqueous suspension for nasal drops, which is easy to prepare, with maintaining superior long-term stability, good redispersibility and high retainability after the intranasal administration, as well as having good after feel. The aqueous suspension for nasal drops comprising containing the following (a), (b), (c), (d), (e) and (f): (a) A compound represented by the following formula (1) wherein R is hydroxyl or cyclohexylcarbonyloxy, or solvate thereof; (b) crystalline cellulose-carmellose sodium 0.1-5% by weight; (c) hydroxypropylcellulose 0.05-1% by weight; (d) nonionic surfactant 0.001-0.2% by weight; (e) moistening agent; and (f) buffering agent.
Claims19
An aqueous suspension for nasal drops comprising containing the following (a), (b), (c), (d), (e) and (f):
- (a) A compound represented by the following formula (1)
- wherein R is hydroxyl or cyclohexylcarbonyloxy, or solvate thereof;
- (b) crystalline cellulose-carmellose sodium 0.1-5% by weight;
- (c) hydroxypropylcellulose 0.05-1% by weight;
- (d) nonionic surfactant 0.001-0.2% by weight;
- (e) moistening agent;
- and
- (f) buffering agent.
Dependencies are inferred from the claim text.