Use of a topical medicament comprising riluzole
AssigneeBiofrontera, Inc.
InventorsMichael Sych, Andreas Goppelt
Life of this patent
Estimating the term…
Abstract
The present invention relates to the use of Riluzole if needed with suitable adjuvants and additives for the production of a medicament for the treatment of diseases characterized by hyperproliferation of keratinocytes and/or T cells, in particular psoriasis and neurodermatitis as well as compositions comprising Riluzole and use thereof.
Claims23
A method of decreasing or inhabiting hyperproliferation of keratinocytes and/or T-cells comprising administering an effective amount of a medicament comprising Riluzole or a pharmaceutically acceptable salt thereof to a subject in need of inhibition of hyperproliferation of keratinocytes and/or T-cells, whereby hyperproliferation of keratinocytes and/or T cells is decreased or inhibited.
A composition comprising Riluzole or a pharmaceutically acceptably salt thereof and one or more additional active ingredients which decrease or inhibit the hyperproliferation of keratinocytes and/or T cells.
A composition comprising Riluzole or a pharmaceutically acceptably salt thereof and one or more calcineurin antagonists.
(canceled)
A topical medicament for transdermal delivery comprising Riluzole or a pharmaceutically acceptable salt thereof and a topical excipient, wherein no significant amount of a dermal penetration enhancer is present in the medicament.
A method of administering Riluzole or a pharmaceutically acceptable salt thereof to a subject in need of treatment for the therapy and/or prevention of neuronal or brain diseases and/or injuries, the method comprising applying a topical medicament comprising Riluzole or a pharmaceutically acceptable salt thereof, whereby Riluzole or a pharmaceutically acceptable salt thereof is administered.
(canceled)
Dependencies are inferred from the claim text.