Method of treating arthritis using lentiviral vectors in gene therapy
AssigneeGenetix Pharmaceuticals, Inc.
InventorsRobert Pawliuk, Philippe Leboulch
Life of this patent
Estimating the term…
Abstract
Novel methods for treating and preventing arthritis, such as rheumatoid arthritis, are disclosed which employ lentiviral gene delivery vectors, including HIV-based lentiviral vectors, to deliver a therapeutic gene to a subject. Lentiviral-based vectors treat arthritis by promoting high-level expression of the transferred therapeutic gene in the target tissue of the subject.
Claims13
A method for treating arthritis comprising delivering to a subject a therapeutic gene using a lentiviral gene delivery vector such that the gene is expressed at sufficient levels and for a sufficient period to treat the subject.
A method for treating arthritis comprising transfecting cells ex vivo with a therapeutic gene using a lentiviral gene delivery vector and administering the cells to a subject.
Dependencies are inferred from the claim text.